A must read for newbies to NMN. Understand NMN in one article: What is NMN? How to eat NMN? How to choose NMN? NMN efficacy and how to take it
In the world of health care, NMN has become a high-profile topic. Many studies have shown that NMN has many potential benefits for our health, such as helping to improve energy metabolism, slowing down the aging rate of the body, and even enhancing the function of our immune system. So, how to take NMN? In this article, we will deconstruct NMN and share some practical suggestions for you, so that you can better understand the effects of NMN and how to take it. Add this article to your book now and let us uncover the mystery of NMN together!
What is NMN?
The full name of NMN is nicotinamide mononucleotide, which is a naturally occurring nucleotide. Before understanding the efficacy of NMN, you must clearly understand how it works.
After NMN is ingested through diet, it can be absorbed by the body and converted into NAD+. Dr. David Sinclair, a biologist at Harvard Medical School, published relevant research in 2013, pointing out that increasing NAD+ levels in the body is beneficial in anti-aging, reversing aging, promoting fat metabolism, improving sleep quality, and preventing diseases. However, as age increases, the NAD+ level in the human body gradually decreases. By the age of 50, the NAD+ level in the body is only half of what it was at the age of 20. Since the human body cannot synthesize NAD+ by itself, it is necessary to supplement NMN to improve the conversion level. Oral NMN supplements can be quickly absorbed by the body, thereby increasing the NAD+ level in the body and achieving anti-aging effects.
Although NMN is a naturally occurring substance, it is found in very small amounts in natural foods such as vegetables, fruits, and meats. Broccoli florets and broccoli, for example, contain only 0.25 to 1.12 mg and 0 to 0.90 mg of NMN per 100 grams. Some popular healthy ingredients, such as avocado and tomatoes, contain 0.36 to 1.60 mg and 0.26 to 0.30 mg of NMN per 100 grams. As for meat, beef contains 0.06 to 0.42 mg of NMN per 100 grams. It can be seen that based on the recommended effective dose of NMN of at least 250 mg per day, it is quite difficult to absorb NMN through daily diet alone.
Who needs to take NMN?
Since the human body's NAD+ level will drop sharply with age, leading to the rapid appearance of aging symptoms, it becomes very difficult to achieve the purpose of anti-aging through daily dietary intake of NMN. Therefore, it is generally recommended to start taking NMN from the age of 30, and younger people (about 20 years old) can also consider starting to take it earlier to maintain their physical condition. For middle-aged and elderly people, the problem of declining NAD+ levels is more serious, so taking NMN becomes even more necessary!
What are the benefits of taking NMN?
The operating principles and mechanisms of NMN are simple and effective, and can make the human body healthy, young and live longer. After ingesting NMN, it can be converted into NAD+, activate Sirtuins1~7 longevity genes and activate mitochondria. At the same time, it can start the process of repairing cellular DNA and help activate stem cells, thereby maintaining the length of telomeres. When these functions are functioning, the body's immune regulation increases, infertility is reduced, and chronic disease prevention is enhanced, thereby delaying aging. NMN can also activate the longevity protein Sirtuins in the body and scavenge free radicals. Long-term use can help restore skin's luster, improve elasticity, reduce fine lines, restore skin's youthful vitality, and achieve the anti-aging beauty effect that women are most concerned about.
Here are some common benefits of taking NMN long-term:
- delay aging
- Improve body function
- Improve sleep quality
- Maintain cellular health
- Promote metabolism
- Enhance immunity
- Improve memory
- Improve fatigue
- maintain muscle performance
- Maintain cardiovascular health
- Prevent skin aging
How to take NMN?
How much NMN does the human body need to take in daily to have effects? According to current human clinical trial results, daily intake of 100 mg to 2000 mg of NMN is within a safe range. For example, if you want to consume 300 mg of NMN daily, you may need to consume more than 26.8 kilograms of broccoli or 71.4 kilograms of beef to absorb this amount from natural foods. Therefore, it is almost impossible to consume enough NMN from natural foods to increase NAD+ levels in the human body. In comparison, oral NMN supplements are more convenient, faster and more effective.
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Weighing less than 90 kg |
Weighing more than 90 kg |
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Under 45 years old |
250 mg |
500 mg |
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45 to 60 years old |
500 mg |
750 mg |
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Over 60 years old |
750 mg |
1000mg |
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Take the recommended dose of NMN daily. |
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What are the side effects of NMN? Can NMN be taken every day?
NMN is a substance that can be taken daily. After rigorous scientific experiments and human clinical testing, NMN products have not found any side effects, confirming that they can be safely and effectively metabolized in the human body. Just follow the instructions and use NMN correctly without worrying about side effects. Many famous people have started using NMN products and invested in their research and development. At the same time, medical and scientific research institutions and universities around the world continue to study NMN, so the effects of oral NMN are becoming more and more reliable.
At present, NMN has been proven to be reliable and effective in resisting skin aging, anti-aging, reverse aging, cell repair, fatigue elimination, improving sleep quality, protecting eyesight, enhancing liver function, improving memory and enhancing immunity. However, there are many NMN products on the market, and it becomes very important to correctly select the appropriate NMN product.
How much NMN should you take?
Recommended doses of NMN range from 100 mg to 2,000 mg daily and are safe. Based on the recommended daily intake of at least 250 mg of NMN, if each oral capsule contains 125 mg of Nicotinamide Mononucleotide, the recommended dosage is 2 to 8 capsules per day. As age increases, the NAD+ level in the human body will gradually decrease. Therefore, the older you get, the dosage of NMN should be adjusted accordingly. In summary, it is recommended that people under 45 years of age consume at least 250 mg of NMN per day; those between 45 and 60 years of age are recommended to consume at least 500 mg of NMN per day; and those over 60 years of age are recommended to consume at least 750 mg of NMN per day.
How long does it take to take NMN to be effective?
According to the results of NMN in human clinical trials, a significant increase in NAD+ levels in the body can be observed as soon as 14 days. Starting from the eighth week, various hormonal data improved, skin condition improved, and physical functions also improved. By the tenth week, insulin sensitivity improves and metabolism improves. Starting from the twelfth week, blood vessel hardness decreased, sleep quality improved, physical strength and exercise capacity increased, and telomere length nearly doubled after 90 days. Therefore, with long-term and balanced intake of NMN, the effect of the product will only get better and better.
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Taking time: |
Effect: |
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2 weeks |
Increased NAD+ levels in the body |
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8 weeks |
Various hormonal data, skin, and various body functions have been improved. |
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10 weeks |
Improved insulin sensitivity and improved metabolism |
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12 weeks |
Reduce blood vessel hardness, improve sleep quality, improve physical strength and exercise endurance |
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about 3 months |
Telomere length nearly doubled |
When is the best time to take NMN?
As a supplement product, the taking time of NMN is relatively not so strict. If the purity of NMN is high enough and it can be quickly absorbed and transformed by the body, the daily dosage and time can be determined according to the needs of the individual's age. For example, an oral capsule containing 125 mg of NMN can be taken as an oral capsule when you wake up in the morning, with additional doses taken every one to three hours to meet your daily needs. There is no restriction on taking NMN before or after meals or on an empty stomach. As long as you take the right amount of NMN supplements correctly, it can bring you unexpected health and anti-aging effects.
How to choose NMN? What do the numbers on the bottle mean?
Some NMN products on the market are marked with numbers such as NMN10000 and NMN15000, but do these numbers mean that the larger the number, the more significant the effect of NMN? In fact, the number on the bottle indicates the total amount of NMN contained in each bottle of NMN product, in milligrams. Taking NMN10000 as an example, it means that the net NMN content in this bottle of product is 10,000 mg; if there are 50 capsules in a bottle, each capsule contains 200 mg of NMN. Therefore, you can calculate by yourself, understand the dosage values in different products, and choose the appropriate product according to your age needs.
Frequently asked questions when purchasing NMN products
NMN (nicotinamide mononucleotide) is one of the derivatives of vitamin B3 (nicotinic acid). It has two isomers, alpha and beta, of which the beta isomer is the active form. Consumers should pay attention to whether NMN products are marked with NMN content and ensure that the purity of NMN products reaches 100%. In addition, NMN’s place of production, brand credibility and certification from authoritative organizations are also important.
First of all, choosing NMN products produced from technologically developed countries or regions is the primary consideration, because NMN is an innovative technology product. The quality of production processes, manufacturing methods, extraction techniques and formulations are critical to ensuring safety and effectiveness. Secondly, strictly select products certified by international authoritative organizations, such as NMN supplements certified by the US Food and Drug Administration (FDA) and US Good Manufacturing Practices (GMP), so as to increase confidence when purchasing and taking them.